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$355,000
ACTIVE Status
Prime Mixed use 3-unit Victorian-style commercial property in a high-visibility corner location! Features currently vacant 1,500 +/- SF retail/service space with bright reception area, large display windows, and flexible layout to suit a variety of business needs. The property includes two residential units: a 2-bedroom($1,030/mo rent thru 10/24/26) with kitchen/living combo and balcony, plus an upper-level efficiency($900/mo rent thru 10/24/26) with open layout and bath. Parking available, strong signage exposure, and convenient location. Updates include $40,000 roof, heating and cooling systems, and new water heater. Ideal for owner-occupants or investors seeking solid cash flow and long-term value!

931 16th Street S, La Crosse

Listing courtesy of eXp Realty LLC.

$2,583
ACTIVE Status
Approximately 1550 sq feet of main floor store frontage right on 5th and Main with parking! Utilities included. This is a sub-lease listing lease agreement for current tenant.

444 Main Street Unit 102, La Crosse

Listing courtesy of eXp Realty LLC.

$1,500
ACTIVE Status
Position your business for success in this high-visibility location offering exceptional exposure and steady traffic flow. This approximately 2,700 sq ft space features a bright and welcoming reception or office area, complemented by large display windows that provide excellent natural light and showcase potential. Whether you're looking to expand or establish a new presence, this versatile space offers both functionality and convenience. Main level and lower level included! Offered at $1,500 per month, this is a great opportunity to secure an affordable and highly visible commercial location right on 16th and Jackson! Seller open to selling building for $360,000. 2BR and Studio above. New $40,000 roof and central air system.

1601 Jackson Street, La Crosse

Listing courtesy of eXp Realty LLC.

$1,300
ACTIVE Status
Prime downtown La Crosse commercial lease opportunity at 515 Main St. Approx. 1,007 sq ft space offers strong visibility and steady foot traffic. Ideal for retail or boutique use with flexible layout and storefront presence. NNN lease at $15.50 per sq ft ($1,300/month) plus CAM $208/month, total rent $1,508/month. Current tenant in place through May 2026. Agent Owned

515 Main Street, La Crosse

Listing courtesy of eXp Realty LLC.

$499,000
ACTIVE Status
Turn-key professional office or behavioral health facility with excellent visibility on Jackson St in La Crosse. This 2,346 SF bi-level building was completely renovated in 2023 and shows in like-new condition. Functional layout includes reception areas, multiple private rooms/offices, kitchen, dining/common space, and restrooms on both levels. Ideal for medical, counseling, clinic, or professional service users. Property offers off-street parking and convenient access to Mayo Clinic Health System, Viterbo University, and downtown La Crosse. Appraisal on file dated 12/13/2024 supporting a $645,000 value. Move-in ready opportunity for an owner-occupant or investor.

1720 Jackson Street, La Crosse

Listing courtesy of Castle Realty, LLC.

$?
ACTIVE Status
Showcase your business in this turn key corner suite! Features include reception area, private offices. Included in your rent is heat, air, electricity, taxes, parking and common area maintenance. Join the professional group at the 600 building!

600 3rd Street N Unit Suite 202, La Crosse

Listing courtesy of Cindy Gerke & Associates.

$799,000
6 Beds ⋅ 5 Baths ⋅ ACTIVE Status
Own a piece of LaCrosse History - and one of the oldest homes on the market in LaCrosse County - with this pre-Civil War Queen Anne architecture home, located in the historic Cass/King Street zone. Home is well preserved with lots of character & charm, including beautiful hardwood floors (**Main Level Hardwood Flooring Refinished August 2026**), carved woodwork, and 10-11' ceilings. 8' pocket doors, crown molding, and stained-glass windows. The upper level is accessible from two staircases with 5 bedrooms, 3 bathrooms and laundry. The 3rd story offers an additional 1600 square feet cleaned and unfinished with additional potential. A guest suite lofts above the garage... walking distance to UW-L, Viterbo, and Western Technical College, as well as Downtown LaCrosse.

928 King Street, La Crosse

Listing courtesy of Century 21 Affiliated.

$269,900
2 Beds ⋅ 2 Baths ⋅ ACTIVE Status
ELEGANT OPEN CONCEPT RANCH STYLE CONDO! ENJOY THE EASE OF LIVING AT 5TH WARD CONDOS-NEWER CENTRALLY LOCATED CONDO DEVELOPMENT! FEATURES: LIVING RM W/LOVELY FIREPLACE (DISPLAY/TV SPACE), MODERN KITCHEN (2-TIER BREAKFAST BAR, QUARTZ, STAINLESS APPLCS, SUBWAY TILE), AMPLE DINING, CONVENIENT MN FLR LAUNDRY, SOLID SIX PANEL DRS, EN-SUITE W/ POCKET DRS TO PRIVATE BATH (WALK-IN SHOWER), COVERED PATIO TO ENJOY MORNING COFFEE, ENERGY EFFICIENT, ATTACHED GARAGE. COMMUNITY AMENITIES: SNOW REMOVAL, LAWN CARE, ON-SITE MAINTENANCE, NEIGHBORHOOD ACTIVITY CENTER (HOST YOUR OWN PARTY OR BUSINESS MEETING, BBQ/GRILL PATIO, FULLY EQUIPPED FITNESS CENTER; SKIP THE GYM MEMBERSHIP). EVERYTHING IS WITHIN REACH: DINING, WALKING TRAILS, UNIVERSITIES, HOSPITALS, SHOPPING & MORE! NO MORE SHOVELING OR MOWING!

1321 Hagar Street, La Crosse

Listing courtesy of RE/MAX Results.

$1,588
ACTIVE Status
THREE MONTHS FREE RENT WITH THREE YEAR LEASE! Don't miss out on this opportunity to move your business to the desirable downtown area! Formerly an MMA gym, this space is just under 3,500 sq. ft. of divisible, customizable business or work shop space right on Main St. in downtown La Crosse. Perfect for an art gallery, showroom, MMA gym, climate-controlled storage, speakeasy, etc! Space has a street level private entrance for your business advertising. Private bath and kitchenette. $1,588/mo. Lease term negotiable. Brand new forced air heating and cooling system. Tenants pay utilities. NO CAM CHARGES! Agent Owned

511 Main Street Unit LL, La Crosse

Listing courtesy of eXp Realty LLC.

$1,600,000
ACTIVE Status
YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR CUSTOMERS, EASY ACCESS TO INTERSTATE/COMMERCE HUB, PLENTY OF PARKING/BUILDABLE SPACE. THERE IS AN EXISTING FUNCTIONAL 5000 SF BRICK BUILDING ON THE .71 ACRE SITE. BUILD OUT TO SUIT YOU AND YOUR VALUED CUSTOMERS NEEDS! SUPER LOCATION; LOCATED AT THE BASE OF THE MISSISSIPPI BRIDGE FROM WEST TO GREET YOUR MINNESOTA CLIENTS & EASY ACCESS FOR YOUR COULEE REGION CLIENTS. BRING YOUR IDEAS, YOU CAN NOT FIND ACREAGE OF THIS SIZE IN A LOCATION LIKE THIS!

529 4th Street S Unit 507-521-529, La Crosse

Listing courtesy of RE/MAX Results.

$2,369
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! This space offers 4 private offices, a kitchenette, and a flexible use room.A fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! $19.95/sq ft. All utilities included! $2,369/mo

700 N 3rd St Unit 204, La Crosse

Listing courtesy of eXp Realty LLC.

$825,000
ACTIVE Status
Rezoned Commercial recently! Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-unit building is now on the market! This property features two office spaces off of 16th St loaded with high end custom cabinetry, multiple office spaces, reception area, tons of space and even a built-in safe! Massive heated warehouse space with a plethora of overhead doors, perfect for storage or a whole other separate tenants space from the two offices. Warehouse space can be rented to multiple different tenants or used for one. 2,400 sq ft high-end upper level apartment(Rents for $2,200)! Custom cabinetry, hardwood floors, rec area and 4BRs! This unique property has everything you need for a business owner occupy, or fantastic investment property! 5-6 total units. Agent Owned

1613 Chase Street, La Crosse

Listing courtesy of eXp Realty LLC.

$1
ACTIVE Status
Versatile 13,700 sq ft building featuring office space, ample storage, private offices, conference rooms, and open floor areas--ideal for a gym, warehouse, or light industrial use. Located in a thriving business park with convenient access and plenty of parking. Perfect turnkey setup for businesses needing a mix of office and operational space. Truck doors and loading dock with additional cold storage. $7,000/month. Utilities to be the repsonsiblity of the tenant.

63 Kraft Street, La Crosse

Listing courtesy of Coldwell Banker Commercial River Valley.

$825,000
ACTIVE Status
Rezoned Commercial recently! Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-use building is now on the market! This property features two office spaces off of 16th St loaded with high end custom cabinetry, multiple office spaces, reception area, tons of space and even a built-in safe! Massive heated warehouse space with a plethora of overhead doors, perfect for storage or a whole other separate tenants space from the two offices. Warehouse space can be rented to multiple different tenants or used for one. And to top it off, a 2,400 sq ft high-end upper level apartment! Custom cabinetry, hardwood floors, rec area and 4BRs! This unique property has everything you need for a business owner occupy, or fantastic investment property! Agent Owned

1613 Chase Street, La Crosse

Listing courtesy of eXp Realty LLC.

$1
ACTIVE Status
Rare opportunity to lease a high-profile vacant corner lot located in the heart of downtown, right at the foot of the bridges connecting Wisconsin and Minnesota. High traffic counts and maximum visibility, making it ideal for retail, food service, or other commercial uses. Ground lease available - rate negotiable. Build-to-suit options considered, or a combination of both ground lease and build-to-suit to fit tenant needs.Don't miss this chance to establish your business in one of the most strategic and high-traffic locations in the region.

601 3rd Street S, La Crosse

Listing courtesy of Coldwell Banker Commercial River Valley.

$4,023
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! Unit features 6 private offices and numerous shared office spaces. Fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! $19.95/sq ft. All utilities included!

700 3rd Street N Unit 206, La Crosse

Listing courtesy of eXp Realty LLC.

$995
ACTIVE Status
Position your business for success with this high-visibility, high-traffic, street-level commercial space located on Main St in downtown La Crosse. Offering approximately 900 sq ft, this space features a spacious main area, private office and/or conference room and a storage area. Whether you are a solopreneur looking for a space of your own or have a small team and want to establish your presence downtown La Crosse, this space might be for you. Agent owned.

610 Main Street, La Crosse

Listing courtesy of eXp Realty LLC.

$3,980
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Updated and professional 4,800 sqft on the 1st floor right next to bathrooms. 8 private offices, break room, reception and cubicles. $9.95/sq ft. Tenant pays electric, no other utility charges, no CAM charges. Limited parking available.

505 King Street Unit #105, La Crosse

Listing courtesy of eXp Realty LLC.

$4,720
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! Unit features 12 office spaces, 2 conference rooms, 20 cubicle spaces, kitchen, and multiple common area work spaces. Space can be modified to suit specific square footage needs, subject to negotiation. Fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! All utilities and services are included in the lease. $4,720/mo.

700 3rd Street N Unit #101, La Crosse

Listing courtesy of eXp Realty LLC.

$1,829
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! Unit features 3-4 office spaces. Fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! $19/sq ft. All utilities included!

700 3rd Street N Unit #103, La Crosse

Listing courtesy of eXp Realty LLC.

$1,650
ACTIVE Status
Very clean and professional office space right across from Trane Park on southside La Crosse. Only a couple blocks off of West Ave. 1,726 sq ft of office space with multiple private offices, reception area, full bath with shower and built-in safe! Signage available, security cameras on entire property. Owner fine with 12-month leases. Option for up to 6,000 sq ft of warehouse space to also lease. $200/mo utility charge. Agent Owned

2425 16th Street S, La Crosse

Listing courtesy of eXp Realty LLC.

$6,000
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Rare opportunity to lease out 12,000 sq ft of space formerly used as a gym! Multiple entrances take you down to this expansive space. Perfect for a gym, martial arts, co-work space, indoor storage, corporate HQ, or lease and sub-lease out to multiple other businesses. Multiple bathrooms and showers along with welcoming front reception area. No CAM charges! Buildout negotiable. $6/sq ft

505 King Street Unit #005, La Crosse

Listing courtesy of eXp Realty LLC.

$1,009
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! 1090 sq ft suite available in the quiet and convenient 505 King building, ideal for a growing business. Wide open space, ready for tenant build out, with a private office space.This was formerly a dance studio. Located on the outskirts of downtown, parking is a breeze! All suites are available at just $9.95 per square foot with no CAM charges. Limited parking available.

505 King Street Unit #125, La Crosse

Listing courtesy of eXp Realty LLC.

$842
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Lock down your affordable office space in one of La Crosse's cornerstone downtown buildings! Owner willing to allow tenant to do buildout and open space up. Tenant pays own electric, limited parking spots available. $9.95/sq ft

505 King Street Unit #128, La Crosse

Listing courtesy of eXp Realty LLC.

$547
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Lock down your affordable office space in one of La Crosse's cornerstone downtown buildings! Owner willing to allow tenant to do buildout and open space up. Tenant pays own electric, limited parking spots available. $9.95/sq ft

505 King Street Unit #117, La Crosse

Listing courtesy of eXp Realty LLC.

$602
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! 608 sq ft suite available in the quiet and convenient 505 King building, ideal for a growing business. Has 2 private offices and a main reception area. Located on the outskirts of downtown, parking is a breeze! All suites are available at just $9.95 per square foot with no CAM charges.Limited parking available.

505 King Street Unit #110, La Crosse

Listing courtesy of eXp Realty LLC.

$1,557
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! 1750 sq ft suite available in the quiet and convenient 505 King building, ideal for a growing business. It has 7 offices, a conference room, and a break room with kitchenette. Located on the outskirts of downtown, parking is a breeze! All suites are available at just $9.95 per square foot with no CAM charges. Limited parking available.

505 King Street Unit #221, La Crosse

Listing courtesy of eXp Realty LLC.

$736
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! 3rd floor suite with a view! One of the few available suites with windows at King on 5th, this suite has 3 offices with a main area. Executive office with windows. Utilities includes except electricity. 715 sq ft space. $9.95/sq ft. Limited parking available.

505 King Street Unit #370, La Crosse

Listing courtesy of eXp Realty LLC.

$1,525
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! This former private executive suite will be sure to wow you! 2nd floor suite has 3-4 offices with a welcome area, reception area and conference. Suite also has its own private bathroom including a shower. Two exit doors. Utilities includes except electricity. 1,761 sq ft space. $9.95/sq ft. Limited parking available.

505 King Street Unit #242, La Crosse

Listing courtesy of eXp Realty LLC.

$2,439
ACTIVE Status
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Lock down your affordable office space in one of La Crosse's cornerstone downtown buildings! This King on 5th space has 3,200 sq ft of 7 offices, conference room, sink area and a front reception area. Owner willing to allow tenant to do buildout and open space up. Tenant pays own electric, limited parking spots available. $9.95/sq ft.

505 King Street Unit #010, La Crosse

Listing courtesy of eXp Realty LLC.

Copyright 2026 WIREX Multiple Listing Service. All rights reserved. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. All information is deemed reliable, but not guaranteed. Information is supplied by seller and other third parties and has not been verified.

Copyright 2026 WIREX Multiple Listing Service. All rights reserved. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. All information is deemed reliable, but not guaranteed. Information is supplied by seller and other third parties and has not been verified.